Article No
AT4454a
Accession Number | P17480 |
Application | WB, IHC, IF |
Article No | AT4454a |
Country Availability | SE, FI, DK, NO, IS, EE, LV, LT, FO, GL |
Clone | 1A2 |
Clone Type | monoclonal |
Conjugation | Unconjugated |
Description | UBTF Antibody |
Recommended Dilution | 1:500~1000 |
Supplier | Abgent |
Entrez Gene ID | 7343 |
Format | Clear, colorless solution in phosphate buffered saline, pH 7.2 . |
Isotype | IgG1 k |
Notes | Upstream binding factor (UBF) is a transcription factor required for expression of the 18S, 5.8S, and 28S ribosomal RNAs, along with SL1 (a complex of TBP (MIM 600075) and multiple TBP-associated factors or 'TAFs'). Two UBF polypeptides, of 94 and 97 kD, exist in the human (Bell et al., 1988 [PubMed 3413483]). UBF is a nucleolar phosphoprotein with both DNA binding and transactivation domains. Sequence-specific DNA binding to the core and upstream control elements of the human rRNA promoter is mediated through several HMG boxes (Jantzen et al., 1990 [PubMed 2330041]). |
Alias Names | Nucleolar transcription factor 1, Autoantigen NOR-90, Upstream-binding factor 1, UBF-1, UBTF, UBF, UBF1 |
Product Type | Antibodies Primary |
Size | 100 µg |
Source / Host | mouse |
Species Reactivity | human, rat |
Substrate / Buffer | Clear, colorless solution in phosphate buffered saline, pH 7.2 . |
Product Page Updated | 2023-11-23T13:40:12.472Z |