Article No
AT4307a
Specifications
| Accession Number | O95985 |
| Application | WB, IF |
| Article No | AT4307a |
| Country Availability | SE, FI, DK, NO, IS, EE, LV, LT, FO, GL |
| Clone | 4H7 |
| Clone Type | monoclonal |
| Conjugation | Unconjugated |
| Description | TOP3B Antibody |
| Recommended Dilution | 1:500~1000 |
| Supplier | Abgent |
| Entrez Gene ID | 8940 |
| Format | Clear, colorless solution in phosphate buffered saline, pH 7.2 . |
| Isotype | IgG2a k |
| Notes | This gene encodes a DNA topoisomerase, an enzyme that controls and alters the topologic states of DNA during transcription. This enzyme catalyzes the transient breaking and rejoining of a single strand of DNA which allows the strands to pass through one another, thus relaxing the supercoils and altering the topology of DNA. The enzyme interacts with DNA helicase SGS1 and plays a role in DNA recombination, cellular aging and maintenance of genome stability. Alternative splicing of the C-terminus of this gene results in three transcript variants which have distinct tissue specificity; however, not all variants have been fully described. |
| Alias Names | DNA topoisomerase 3-beta-1, DNA topoisomerase III beta-1, TOP3B, TOP3B1 |
| Product Type | Antibodies Primary |
| Size | 100 µg |
| Source / Host | mouse |
| Species Reactivity | human |
| Substrate / Buffer | Clear, colorless solution in phosphate buffered saline, pH 7.2 . |
| Product Page Updated | 2023-11-23T13:40:12.472Z |
