Article No
AT2544a
Specifications
| Accession Number | Q15306 |
| Application | WB, IHC |
| Article No | AT2544a |
| Country Availability | SE, FI, DK, NO, IS, EE, LV, LT, FO, GL |
| Clone | 2F2 |
| Clone Type | monoclonal |
| Conjugation | Unconjugated |
| Description | IRF4 Antibody |
| Recommended Dilution | 1:500~1000 |
| Supplier | Abgent |
| Entrez Gene ID | 3662 |
| Format | Clear, colorless solution in phosphate buffered saline, pH 7.2 . |
| Isotype | IgG2a k |
| Notes | The protein encoded by this gene belongs to the IRF (interferon regulatory factor) family of transcription factors, characterized by an unique tryptophan pentad repeat DNA-binding domain. The IRFs are important in the regulation of interferons in response to infection by virus, and in the regulation of interferon-inducible genes. This family member is lymphocyte specific and negatively regulates Toll-like-receptor (TLR) signaling that is central to the activation of innate and adaptive immune systems. A chromosomal translocation involving this gene and the IgH locus, t(6;14)(p25;q32), may be a cause of multiple myeloma. Alternatively spliced transcript variants have been found for this gene. |
| Alias Names | Interferon regulatory factor 4, IRF-4, Lymphocyte-specific interferon regulatory factor, LSIRF, Multiple myeloma oncogene 1, NF-EM5, IRF4, MUM1 |
| Product Type | Antibodies Primary |
| Protocol | 1:500~1000 |
| Size | 100 µg |
| Source / Host | mouse |
| Species Reactivity | human |
| Substrate / Buffer | Clear, colorless solution in phosphate buffered saline, pH 7.2 . |
| Product Page Updated | 2023-11-23T13:40:12.472Z |
