Article No
AT2523a
Accession Number | P40189 |
Application | WB |
Article No | AT2523a |
Country Availability | SE, FI, DK, NO, IS, EE, LV, LT, FO, GL |
Clone | 4A4 |
Clone Type | monoclonal |
Conjugation | Unconjugated |
Description | IL6ST Antibody |
Recommended Dilution | 1:500~1000 |
Supplier | Abgent |
Entrez Gene ID | 3572 |
Format | Clear, colorless solution in phosphate buffered saline, pH 7.2 . |
Isotype | IgG2a k |
Notes | The protein encoded by this gene is a signal transducer shared by many cytokines, including interleukin 6 (IL6), ciliary neurotrophic factor (CNTF), leukemia inhibitory factor (LIF), and oncostatin M (OSM). This protein functions as a part of the cytokine receptor complex. The activation of this protein is dependent upon the binding of cytokines to their receptors. vIL6, a protein related to IL6 and encoded by the Kaposi sarcoma-associated herpesvirus, can bypass the interleukin 6 receptor (IL6R) and directly activate this protein. Knockout studies in mice suggest that this gene plays a critical role in regulating myocyte apoptosis. Alternatively spliced transcript variants encoding distinct isoforms have been described. A related pseudogene has been identified on chromosome 17. |
Alias Names | Interleukin-6 receptor subunit beta, IL-6 receptor subunit beta, IL-6R subunit beta, IL-6R-beta, IL-6RB, CDw130, Interleukin-6 signal transducer, Membrane glycoprotein 130, gp130, Oncostatin-M receptor subunit alpha, CD130, IL6ST |
Product Type | Antibodies Primary |
Protocol | 1:500~1000 |
Size | 100 µg |
Source / Host | mouse |
Species Reactivity | human |
Substrate / Buffer | Clear, colorless solution in phosphate buffered saline, pH 7.2 . |
Product Page Updated | 2023-11-23T13:40:12.472Z |