Article No
ASJ-NU4E5Q-300
Application | WB |
Article No | ASJ-NU4E5Q-300 |
Biosite Brand | Biosite |
Country Availability | all |
Clone Type | polyclonal |
Concentration | 3 mg/ml |
Conjugation | Unconjugated |
Description | Anti-TNF antibody |
Recommended Dilution | WB 1:500-1:2000 |
Supplier | Nordic Biosite |
Entrez Gene ID | 7124 |
Gene Symbol | TNF |
Immunogen | Purified recombinant human TNF alpha produced in E. coli. |
Isotype | IgG |
Localization | Cell membrane Tumor necrosis factor, membrane form: Membrane. Single-pass type II membrane protein.. Tumor necrosis factor, soluble form: Secreted.. C-domain 1: Secreted.. C-domain 2: Secreted. |
Notes | Goat polyclonal antibody to TNF alpha. TNF-alpha is produced by a variety of immune cells including NK cells, B cells, T cells and macrophages. It is multifunctional proinflammatory cytokine that belongs to the tumour necrosis factor (TNF) superfamily. It can bind to, and thus functions through its receptors TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. It is involved in the regulation of several processes including lipid metabolism cell differentiation and proliferation, coagulation and apoptosis. It has been implicated in a variety of diseases, including cancer and autoimmune diseases. |
Alias Names | Tumor necrosis factor (Cachectin) (TNF-alpha) (Tumor necrosis factor ligand superfamily member 2) (TNF-a) [Cleaved into: Tumor necrosis factor, membrane form (N-terminal fragment) (NTF); Intracellular domain 1 (ICD1); Intracellular domain 2 (ICD2); C-doma |
Previous Article No | ASJ-8C8D11 |
Product Type | Antibodies Primary |
Protocol | Western blot 1:500-1:2,000 Immunofluorescence ND Immunohistochemistry (paraffin) ND Immunohistochemistry (frozen) ND |
Purification | Affinity Purified |
Size | 300ug |
Source / Host | goat |
Species Reactivity | dog/canine, human, monkey, mouse, rat |
Storage | -20°C, 4°C |
Substrate / Buffer | PBS, 20% glycerol and 0.05% sodium azide. |
Technical Specifications | Goat polyclonal against TNF alpha |
UniProt Number | P01375 |
Product Page Updated | 2024-04-18T09:14:23.014Z |