Article No
ASJ-M64EFF-50
Application | ICC, IF, IHC, WB |
Article No | ASJ-M64EFF-50 |
Biosite Brand | Biosite |
Country Availability | all |
Clone Type | polyclonal |
Conjugation | Unconjugated |
Description | Anti-IL18R1 antibody (19-320) |
Recommended Dilution | ICC 1:50-1:200, IF 1:50-1:200, IHC-P 1:50-1:200, WB 1:500-1:1000 |
Supplier | Nordic Biosite |
Entrez Gene ID | 8809 |
Gene Symbol | IL18R1 |
Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 19-320 of human IL18R1/IL-18 R alpha (NP_003846.1). |
Isotype | IgG |
Localization | Membrane |
Notes | The protein encoded by this gene is a cytokine receptor that belongs to the interleukin 1 receptor family. This receptor specifically binds interleukin 18 (IL18), and is essential for IL18 mediated signal transduction. IFN-alpha and IL12 are reported to induce the expression of this receptor in NK and T cells. This gene along with four other members of the interleukin 1 receptor family, including IL1R2, IL1R1, ILRL2 (IL-1Rrp2), and IL1RL1 (T1/ST2), form a gene cluster on chromosome 2q. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. |
Alias Names | Anti-Interleukin-18 Receptor 1 antibody, Anti-Il-18r-1 antibody, Anti-Il-18r1 antibody, Anti-Cd218 Antigen-Like Family Member A antibody, Anti-Cdw218a antibody, Anti-Il1 Receptor-Related Protein antibody, Anti-Il-1rrp antibody, Anti-Il1r-Rp antibody, Anti-Interleukin-18 Receptor Alpha antibody, Anti-Il-18r-Alpha antibody, Anti-Il-18ralpha antibody, Anti-Cd Antigen Cd218a antibody, Anti-IL18R1 IL1RRP antibody |
Previous Article No | ASJ-2718BB |
Product Type | Antibodies Primary |
Protocol | WB: 1:500-1:1000 IF: 1:50-1:200 |
Purification | Affinity Purified |
Size | 50ul |
Source / Host | rabbit |
Species Reactivity | human, mouse, rat |
Storage | -20°C |
Substrate / Buffer | PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Tissue Specificity | Highly expressed in leukocytes, spleen, lung. Also expressed, but at lower levels, in liver, small intestine, colon, prostate, thymus, placenta, and heart. Specifically coexpressed with IL18R1 in Th1 cells. |
UniProt Number | Q13478 |
Product Page Updated | 2024-04-18T09:14:23.014Z |