Article No
ASB-LVRQV8-0.1
Rat Anti-Mouse CD38-PE
Rat Anti-Mouse CD38-PE
Antibodies Primary
Specifications
| NCBI Number | 12494 |
| Application | FC |
| Article No | ASB-LVRQV8-0.1 |
| Biosite Brand | Biosite |
| Country Availability | all |
| Clone | NIMR-5 |
| Clone Type | monoclonal |
| Concentration | 0.1 mg/mL |
| Conjugation | PE |
| Description | Rat Anti-Mouse CD38-PE |
| Supplier | Nordic Biosite |
| Format | Liquid |
| Immunogen | BCL1 plasma membrane glycoproteins |
| Isotype | IgG2a |
| Notes | Murine CD38, a type II transmembrane glycoprotein, is a bifunctional ectoenzyme capable of catabolizing nicotinamide adenine dinucleotide (NAD+) to cyclic ADP-ribose (cADPR) and then hydrolyzing cADPR to adenosine diphosphoribose (ADPR). It is expressed at high levels on the surface of peripheral B-lineage cells and at low density on germinal center B cells from unimmunized mice. It has also been reported to be expressed at moderate levels on NK cells, a proportion of peripheral T cells, and a subpopulation of thymocytes which are mostly TCR gamma/delta+, CD4-, CD8-. Murine CD38 is also expressed by all Mac-1+ macrophages in the peritoneal cavities of unimmunized mice, but not by unstimulated bone-marrow-derived macrophages. Monoclonal antibodies to CD38 have been shown to induce B and T cell proliferation, protect B cells from apoptosis, and inhibit B lymphopoiesis. |
| Alias Names | T10, ADP-ribosyl cyclase, cyclic ADP-ribose hydrolase |
| Previous Article No | ASB-QGIG2P-0.1, ASB-163509, ASB-LVRQV8-0.1 |
| Product Type | Antibodies Primary |
| Shipping Information | Ambient Temperature |
| Size | 0.1 mg |
| Source / Host | rat |
| Species Reactivity | mouse |
| Storage | 2-8°C |
| Substrate / Buffer | Phosphate buffered saline containing < 0.1% sodium azide and a stabilizer |
| Swiss-Prot No | P56528 |
| Product Page Updated | 2024-01-11T10:51:07.446Z |
| Volume | 1.0 mL |
