Article No
ASB-LP2183-0.1
Rat Anti-Mouse CD4-APC/CY7
Rat Anti-Mouse CD4-APC/CY7
Antibodies Primary
Specifications
| NCBI Number | 12504 |
| Application | FC |
| Article No | ASB-LP2183-0.1 |
| Biosite Brand | Biosite |
| Country Availability | all |
| Clone | GK1.5 |
| Clone Type | monoclonal |
| Concentration | 0.1 mg/mL |
| Conjugation | APC/Cy7 |
| Description | Rat Anti-Mouse CD4-APC/CY7 |
| Supplier | Nordic Biosite |
| Format | Liquid |
| Immunogen | Mouse CTL clone V4 |
| Isotype | IgG2b |
| Notes | CD4 is a type I transmembrane glycoprotein expressed on most thymocytes and the helper/inducer subpopulation of mature T lymphocytes of all mouse strains tested. CD4 has also been detected at low density on pluripotent hematopoietic stem cells, bone marrow myeloid precursors, and intrathymic lymphoid precursors. The CD4 antigen functions as a co-receptor, interacting with class II major histocompatability complex (MHC) molecules in the recognition of foreign antigens by T cells. In vivo and in vitro treatment with the GK1.5 monoclonal antibody effectively depletes CD4+ cells. GK1.5 also blocks helper T cell responses to MHC class II antigens, including cytolysis, proliferation, allogeneic B cell help, and release of lymphokines. |
| Alias Names | L3T4, Ly-4 |
| Previous Article No | ASB-154019, ASB-LP2183-0.1 |
| Product Type | Antibodies Primary |
| Shipping Information | Ambient Temperature |
| Size | 0.1 mg |
| Source / Host | rat |
| Species Reactivity | mouse |
| Storage | 2-8°C |
| Substrate / Buffer | Phosphate buffered saline containing < 0.1% sodium azide and a stabilizer |
| Swiss-Prot No | P06332 |
| Product Page Updated | 2024-01-11T10:51:07.446Z |
| Volume | 1.0 mL |
