Article No
ASB-SOOU51-0.5
Mouse Anti-Mouse H-2Kd/H-2Dd-BIOT
Mouse Anti-Mouse H-2Kd/H-2Dd-BIOT
Antibodies Primary
Specifications
| NCBI Number | 14972, 14964 |
| Application | FC, ICC, EM, IP |
| Article No | ASB-SOOU51-0.5 |
| Biosite Brand | Biosite |
| Country Availability | all |
| Clone | 34-1-2S |
| Clone Type | monoclonal |
| Concentration | 0.5 mg/mL |
| Conjugation | Biotin |
| Description | Mouse Anti-Mouse H-2Kd/H-2Dd-BIOT |
| Supplier | Nordic Biosite |
| Format | Liquid |
| Immunogen | BDF1 mouse splenocytes |
| Isotype | IgG2a |
| Notes | The "classical" MHC Class I molecules are histocompatibility antigens encoded by the H-2 gene complex and consist of heterodimers of highly polymorphic alpha chains noncovalently associated with the invariant beta2-microglobulin. These antigens are expressed on most nucleated cells but expression varies on different cell types. MHC Class I molecules present endogenously synthesized peptides to CD8+ T lymphocytes, which are usually cytotoxic T cells. MHC Class I antigens expressed on thymic epithelial cells regulate the positive and negative selection of CD8+ T cells during T cell ontogeny. The monoclonal antibody 34-1-2S binds to a common determinant in the alpha3 domains of H-2Kd and H-2Dd in the presence or absence of beta2 microglobulin. It cross reacts with the alpha3 domain of H-2Kb. |
| Alias Names | MHC Class I |
| Previous Article No | ASB-191108, ASB-SOOU51-0.5 |
| Product Type | Antibodies Primary |
| Shipping Information | Ambient Temperature |
| Size | 0.5 mg |
| Source / Host | mouse |
| Species Reactivity | mouse |
| Storage | 2-8°C |
| Substrate / Buffer | Phosphate buffered saline containing < 0.1% sodium azide |
| Swiss-Prot No | P01902, P01900 |
| Product Page Updated | 2024-01-11T10:51:07.446Z |
| Volume | 1.0 mL |
