Article No
ASB-4E0PO6-0.5
NCBI Number | 16401, 16421 |
Application | FC, IHC, Block, IP |
Article No | ASB-4E0PO6-0.5 |
Biosite Brand | Biosite |
Country Availability | all |
Clone | DATK32 |
Clone Type | monoclonal |
Concentration | 0.5 mg/mL |
Conjugation | LEAF |
Description | Rat Anti-Mouse LPAM-1-LE/AF |
Supplier | Nordic Biosite |
Format | Liquid |
Immunogen | AKR/Cum mouse T lymphoma cell line TK-1 |
Isotype | IgG2a |
Notes | The lymphocyte Peyer's patch adhesion molecule (LPAM-1), also known as integrin alpha4/beta7, is a member of the integrin family of cell surface receptors. It is expressed primarily on mucosal lymphocytes but is also present on NK cells and eosinophils. The alpha4/beta7 heterodimer mediates the binding of lymphocytes to its ligand, mucosal vascular addressin (MAdCAM-1) on the high endothelial venules, thereby directing the homing of lymphocytes into Peyer's patches and intestinal lamina propria. The monoclonal antibody DATK32 recognizes a conformational epitope on the heterodimer. |
Alias Names | Integrin α4β7, lymphocyte Peyer's patch adhesion molecule |
Previous Article No | ASB-187014, ASB-4E0PO6-0.5 |
Product Type | Antibodies Primary |
Shipping Information | Dry Ice |
Size | 0.5 mg |
Source / Host | rat |
Species Reactivity | mouse |
Storage | -20°C |
Substrate / Buffer | Phosphate buffered saline, pH 7.4 |
Swiss-Prot No | Q00651, P26011 |
Product Page Updated | 2024-01-11T10:51:07.446Z |
Volume | 1.0 mL |