Article No
ASB-9JUFJ9-0.1
Hamster Anti-Mouse Ly-49C/F/H/I-PE
Hamster Anti-Mouse Ly-49C/F/H/I-PE
Antibodies Primary
Specifications
| NCBI Number | 16634, 16637, 16639, 16640 |
| Application | FC |
| Article No | ASB-9JUFJ9-0.1 |
| Biosite Brand | Biosite |
| Country Availability | all |
| Clone | 14B11 |
| Clone Type | monoclonal |
| Concentration | 0.1 mg/mL |
| Conjugation | PE |
| Description | Hamster Anti-Mouse Ly-49C/F/H/I-PE |
| Supplier | Nordic Biosite |
| Format | Liquid |
| Immunogen | IL-2 activated natural killed (A-LAK) cells from C57BL/6 mice |
| Isotype | IgG |
| Notes | The monoclonal antibody 14B11 reacts with murine Ly49C, Ly49F, Ly49H, and Ly49I, members of the lectin-like homodimeric Ly49 family of cell surface receptors. Mouse Ly49 receptors exhibit allelic specificity for MHC class I Ia molecules and are thought to serve to prevent natural killer (NK) cells from attacking normal cells while allowing them to attack infected or transformed cells in which class I molecules have been downregulated. These inhibitory receptors are also expressed on a subpopulation of mouse CD8+ T cells. The 14B11 antibody stains ~90% of NK1.1+CD3- splenocytes and ~6% of CD8+ spleen cells from C57BL/6 mice. The antibody also stains 30-80% of NK1.1+CD3- splenocytes in other mouse strains tested (BALB/c, C3H, 129, SJL, AKR/J). |
| Alias Names | Ly-49 |
| Previous Article No | ASB-EWA8UX-0.1, ASB-180109, ASB-9JUFJ9-0.1 |
| Product Type | Antibodies Primary |
| Shipping Information | Ambient Temperature |
| Size | 0.1 mg |
| Source / Host | hamster |
| Species Reactivity | mouse |
| Storage | 2-8°C |
| Substrate / Buffer | Phosphate buffered saline containing < 0.1% sodium azide and a stabilizer |
| Swiss-Prot No | Q64329, Q60653, Q60682, Q2TJJ8 |
| Product Page Updated | 2024-01-11T10:51:07.446Z |
| Volume | 1.0 mL |
