Article No
ASB-7DYSYG-0.5
NCBI Number | 16634, 16637, 16639, 16640 |
Application | FC, CyTOF |
Article No | ASB-7DYSYG-0.5 |
Biosite Brand | Biosite |
Country Availability | all |
Clone | 14B11 |
Clone Type | monoclonal |
Concentration | 0.5 mg/mL |
Conjugation | Unconjugated |
Description | Hamster Anti-Mouse Ly-49C/F/H/I-UNLB |
Supplier | Nordic Biosite |
Format | Liquid |
Immunogen | IL-2 activated natural killed (A-LAK) cells from C57BL/6 mice |
Isotype | IgG |
Notes | The monoclonal antibody 14B11 reacts with murine Ly49C, Ly49F, Ly49H, and Ly49I, members of the lectin-like homodimeric Ly49 family of cell surface receptors. Mouse Ly49 receptors exhibit allelic specificity for MHC class I Ia molecules and are thought to serve to prevent natural killer (NK) cells from attacking normal cells while allowing them to attack infected or transformed cells in which class I molecules have been downregulated. These inhibitory receptors are also expressed on a subpopulation of mouse CD8+ T cells. The 14B11 antibody stains ~90% of NK1.1+CD3- splenocytes and ~6% of CD8+ spleen cells from C57BL/6 mice. The antibody also stains 30-80% of NK1.1+CD3- splenocytes in other mouse strains tested (BALB/c, C3H, 129, SJL, AKR/J). |
Alias Names | Ly-49 |
Previous Article No | ASB-2KYWU9-0.5, ASB-180101, ASB-7DYSYG-0.5 |
Product Type | Antibodies Primary |
Shipping Information | Ambient Temperature |
Size | 0.5 mg |
Source / Host | hamster |
Species Reactivity | mouse |
Storage | 2-8°C |
Substrate / Buffer | Borate buffered saline, pH 8.2 |
Swiss-Prot No | Q64329, Q60653, Q60682, Q2TJJ8 |
Product Page Updated | 2024-01-11T10:51:07.446Z |
Volume | 1.0 mL |