Article No
ASB-WTJA9F-0.2
Rat Anti-Mouse CD80-PE
Rat Anti-Mouse CD80-PE
Antibodies Primary
Specifications
| NCBI Number | 12519 |
| Application | FC |
| Article No | ASB-WTJA9F-0.2 |
| Biosite Brand | Biosite |
| Country Availability | all |
| Clone | 1G10 |
| Clone Type | monoclonal |
| Concentration | 0.1 mg/mL |
| Conjugation | PE |
| Description | Rat Anti-Mouse CD80-PE |
| Supplier | Nordic Biosite |
| Format | Liquid |
| Immunogen | Activated 5C2 cells |
| Isotype | IgG2a |
| Notes | CD80 (B7-1) is a type I transmembrane glycoprotein and a member of the immunoglobulin superfamily of cell surface receptors. It is constitutively expressed by dendritic cells, monocytes, and peritoneal macrophages. Expression of CD80 on B cells is upregulated after activation by various means including stimulation by LPS, IL-4, and surface Ig receptor crosslinking with peak expression occurring between 48 and 72 hours post-activation. The interaction of CD80 with its ligands, CD28 and CD152 (CTLA-4), provides a potent costimulatory signal for T cells activated through the CD3/T cell receptor complex. The monoclonal antibody 1G10 blocks binding of CTLA-4 to CD80 but it does not block stimulation of T cells by natural antigen-presenting cells. |
| Alias Names | B7-1, Ly-53 |
| Previous Article No | ASB-173009L, ASB-WTJA9F-0.2 |
| Product Type | Antibodies Primary |
| Shipping Information | Ambient Temperature |
| Size | 0.2 mg |
| Source / Host | rat |
| Species Reactivity | mouse |
| Storage | 2-8°C |
| Substrate / Buffer | Phosphate buffered saline containing < 0.1% sodium azide and a stabilizer |
| Swiss-Prot No | Q00609 |
| Product Page Updated | 2024-01-11T10:51:07.446Z |
| Volume | 2.0 mL |
