Article No
ASB-0IZNHF-0.5
Rat Anti-Mouse CD54-UNLB
Rat Anti-Mouse CD54-UNLB
Antibodies Primary
Specifications
| NCBI Number | 15894, 396750 |
| Application | FC, IHC, ICC, WB, IP, Block |
| Article No | ASB-0IZNHF-0.5 |
| Biosite Brand | Biosite |
| Country Availability | all |
| Clone | YN1/1.7.4 |
| Clone Type | monoclonal |
| Concentration | 0.5 mg/mL |
| Conjugation | Unconjugated |
| Description | Rat Anti-Mouse CD54-UNLB |
| Supplier | Nordic Biosite |
| Format | Liquid |
| Immunogen | Mouse NS-1 cells |
| Isotype | IgG2b |
| Notes | CD54, a member of the immunoglobulin superfamily of cell surface receptors and also known as Intercellular Adhesion Molecule-1 (ICAM-1), is a type I transmembrane glycoprotein that mediates important cell/cell interactions. CD54 is expressed on endothelial cells, dendritic cells, keratinocytes, and lymphocytes. Its expression is upregulated by inflammatory mediators such as IFN-gamma, IL-1, TNF-alpha, lipopolysaccharide, and phorbol esters. Endothelial CD54 contributes to the extravasation of leukocytes from blood vessels, particularly in areas of inflammation. CD54 on antigen-presenting cells contributes to antigen-specific T-cell activation, presumably by enhancing interactions between T cell and antigen-presenting cells. These adhesion reactions are mediated via the binding of CD54 to its major ligands, LFA-1 and Mac-1. |
| Alias Names | ICAM-1, Ly-47 |
| Previous Article No | ASB-AS642H-0.5, ASB-170101, ASB-0IZNHF-0.5 |
| Product Type | Antibodies Primary |
| Shipping Information | Ambient Temperature |
| Size | 0.5 mg |
| Source / Host | rat |
| Species Reactivity | mouse |
| Storage | 2-8°C |
| Substrate / Buffer | Borate buffered saline, pH 8.2 |
| Swiss-Prot No | P13597 |
| Product Page Updated | 2024-02-02T14:39:29.088Z |
| Volume | 1.0 mL |
