Article No
ASB-YUQPM6-0.2
Rat Anti-Mouse CD23-PE
Rat Anti-Mouse CD23-PE
Antibodies Primary
Specifications
| NCBI Number | 14128 |
| Application | FC |
| Article No | ASB-YUQPM6-0.2 |
| Biosite Brand | Biosite |
| Country Availability | all |
| Clone | 2G8 |
| Clone Type | monoclonal |
| Concentration | 0.1 mg/mL |
| Conjugation | PE |
| Description | Rat Anti-Mouse CD23-PE |
| Supplier | Nordic Biosite |
| Format | Liquid |
| Immunogen | FceR isolated from B cell lymphoma cell line M12.4.5 |
| Isotype | IgG2a |
| Notes | The CD23 antigen is the low affinity IgE Fc receptor, which is a 45-49 kDa protein with 38 and 28 kDa fragments. It is expressed on most mature, conventional B cells (but not on peritoneal CD5+ B cells) and can also be found on the surface of T cells, macrophages and platelets. It is distinct from the high affinity IgE receptors found on basophils and mast cells which mediate allergic reactions. The low affinity receptors are thought to play a role in isotype specific immunoregulation. The regulation of CD23 surface expression appears to be integral with the complex IgE system which involves interactions of cells, cytokines, antibodies and regulatory factors. CD23 has been described as a "membrane bound cytokine," in that the soluble cleavage products of CD23 are themselves able to act as cytokines in vitro. |
| Alias Names | FcεRII, BLAST-2, low affinity IgE receptor, Ly-42 |
| Previous Article No | ASB-158509L, ASB-YUQPM6-0.2 |
| Product Type | Antibodies Primary |
| Shipping Information | Ambient Temperature |
| Size | 0.2 mg |
| Source / Host | rat |
| Species Reactivity | mouse |
| Storage | 2-8°C |
| Substrate / Buffer | Phosphate buffered saline containing < 0.1% sodium azide and a stabilizer |
| Swiss-Prot No | P20693 |
| Product Page Updated | 2024-01-11T10:51:07.446Z |
| Volume | 2.0 mL |
