Article No
ASB-F9JXMR-0.5
Rat Anti-Mouse CD5-BIOT
Rat Anti-Mouse CD5-BIOT
Antibodies Primary
Specifications
| NCBI Number | 12507 |
| Application | FC, IP, WB |
| Article No | ASB-F9JXMR-0.5 |
| Biosite Brand | Biosite |
| Country Availability | all |
| Clone | B19.1 |
| Clone Type | monoclonal |
| Concentration | 0.5 mg/mL |
| Conjugation | Biotin |
| Description | Rat Anti-Mouse CD5-BIOT |
| Supplier | Nordic Biosite |
| Format | Liquid |
| Isotype | IgG2a |
| Notes | CD5, also known as Lyt-1, is a monomeric type I transmembrane glycoprotein expressed on thymocytes, T lymphocytes, and a subset of B lymphocytes, but not on natural killer (NK) cells. It has been identified as the major ligand of the B-cell antigen CD72. The frequency of CD5+ B cells exhibits strain-dependent variation, and the phenotypic, anatomical, functional, developmental, and pathological characteristics of the CD5+ B cells suggest that they may represent a distinct lineage, known as B-1 cells. Binding of CD5 on the T cell surface can augment alloantigen- or mitogen-induced lymphocyte proliferation and induces increased cytosolic free calcium, IL-2 secretion, and IL-2R expression. It has been proposed that CD5 negatively regulates signal transduction mediated by the T-cell and B-cell receptors. |
| Alias Names | Lyt-1, Ly-1, Lymphocyte antigen 1, Ly-12, Ly-A, T1, Tp67 |
| Previous Article No | ASB-154508, ASB-F9JXMR-0.5 |
| Product Type | Antibodies Primary |
| Shipping Information | Ambient Temperature |
| Size | 0.5 mg |
| Source / Host | rat |
| Species Reactivity | mouse |
| Storage | 2-8°C |
| Substrate / Buffer | Phosphate buffered saline containing < 0.1% sodium azide |
| Swiss-Prot No | P13379 |
| Product Page Updated | 2024-01-11T10:51:07.446Z |
| Volume | 1.0 mL |
