Article No
ASB-1XL3WZ-0.5
Rat Anti-Mouse CD3ε-LE/AF
Rat Anti-Mouse CD3ε-LE/AF
Antibodies Primary
Specifications
| NCBI Number | 12501 |
| Application | FC, IHC, IP, Depletion, CMCD |
| Article No | ASB-1XL3WZ-0.5 |
| Biosite Brand | Biosite |
| Country Availability | all |
| Clone | C363.29B |
| Clone Type | monoclonal |
| Concentration | 0.5 mg/mL |
| Conjugation | LEAF |
| Description | Rat Anti-Mouse CD3ε-LE/AF |
| Supplier | Nordic Biosite |
| Format | Liquid |
| Immunogen | IL-4 producing Th2 cell lines including D10 |
| Isotype | IgG2b |
| Notes | CD3 epsilon, a member of the immunoglobulin superfamily of cell surface receptors, is comprised of five invariable chain ranging in size from 16-28 kDa and is closely associated with the T cell antigen receptor (TCR). It is expressed on all T cells of all mouse strains. CD3 plays a major role in signaling during antigen recognition, leading to T-cell activation. The monoclonal antibody C363.29B recognizes an epitope on the 25 kDa epsilon chain of the CD3/TCR complex. In the presence of Fc receptor-bearing accessory cells, soluble C363.29B can activate primed and naive T cell in vitro. Immobilized C363.2B9 monoclonal antibody can also activate both normal T lymphocytes and cloned T cell lines provided the appropriate accessory signals are present. The monoclonal antibody is cytolytic, easily used for cell surface staining, and a good immunoprecipitating antibody. |
| Alias Names | CD3 epsilon |
| Previous Article No | ASB-A02G69-0.5, ASB-153514, ASB-1XL3WZ-0.5 |
| Product Type | Antibodies Primary |
| Shipping Information | Dry Ice |
| Size | 0.5 mg |
| Source / Host | rat |
| Species Reactivity | mouse |
| Storage | -20°C |
| Substrate / Buffer | Phosphate buffered saline, pH 7.4 |
| Swiss-Prot No | P22646 |
| Product Page Updated | 2024-01-11T10:51:07.446Z |
| Volume | 1.0 mL |
