Article No
AP7103A-ev
MW | 57848 |
NCBI Number | NP_001265508.1;NP_001265509.1;NP_001607.1 |
Accession Number | P27037 |
Application | WB |
Article No | AP7103A-ev |
Country Availability | SE, FI, DK, NO, IS, EE, LV, LT, FO, GL |
Clone | RB08169-08170 |
Clone Type | polyclonal |
Conjugation | Unconjugated |
Description | ACVR2A Antibody (N-term) |
Recommended Dilution | 1:1000 |
Supplier | Abgent |
Entrez Gene ID | 92 |
Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS. |
Isotype | IgG |
Keywords | Primary Antibodies;Metabolism;Signal Transduction |
Notes | ACVR2A is an activin A type II receptor. Activins are dimeric growth and differentiation factors which belong to the transforming growth factor-beta (TGF-beta) superfamily of structurally related signaling proteins. Activins signal through a heteromeric complex of receptor serine kinases which include at least two type I (I and IB) and two type II (II and IIB) receptors. These receptors are all transmembrane proteins, composed of a ligand-binding extracellular domain with cysteine-rich region, a transmembrane domain, and a cytoplasmic domain with predicted serine/threonine specificity. Type I receptors are essential for signaling; and type II receptors are required for binding ligands and for expression of type I receptors. Type I and II receptors form a stable complex after ligand binding, resulting in phosphorylation of type I receptors by type II receptors. Type II receptors are considered to be constitutively active kinases. |
Alias Names | Activin receptor type-2A, Activin receptor type IIA, ACTR-IIA, ACTRIIA, ACVR2A, ACVR2 |
Product Type | Antibodies Primary |
Research Area | Metabolism |
Size | 80 µl |
Source / Host | rabbit |
Species Reactivity | human, mouse |
Substrate / Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS. |
Technical Specifications | This ACVR2A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 2-29 amino acids from the N-terminal region of human ACVR2A. |
Product Page Updated | 2023-11-23T14:38:54.086Z |