Antibodies Primary

NRG2

NEW
NRG2 Antibody (C-term)

Article No

AP6223a

Application

WB

Species Reactivity

human

Size

400 µl

Clone

RB1278

Source / Host

rabbit

Product insert

Suggested protocols

Specifications

MW 91679
NCBI Number NP_001171864.1;NP_004874.1;NP_053584.1;NP_053585.1;NP_053586.1
Application WB
Article No AP6223a
Country Availability SE, FI, DK, NO, IS, EE, LV, LT, FO, GL
Clone RB1278
Clone Type polyclonal
Description NRG2 Antibody (C-term)
Recommended Dilution 1:1000
Supplier Abgent
Isotype Ig
Keywords Primary Antibodies;Neuroscience;Signal Transduction
Notes Neuregulin 2 (NRG2) is a novel member of the neuregulin family of growth and differentiation factors. Through interaction with the Erbb family of receptors, NRG2 induces the growth and differentiation of epithelial, neuronal, glial, and other types of cells. The gene consists of 12 exons and the genomic structure is similar to that of neuregulin 1 (NRG1), another member of the neuregulin family of ligands. NRG1 and NRG2 mediate distinct biological processes by acting at different sites in tissues and eliciting different biological responses in cells. There are six NRG2 alternatively spliced transcripts which are variable between the epidermal growth factor-like (EGF-like) and the transmembrane domains. The gene is located close to the region for demyelinating Charcot-Marie-Tooth disease locus, but is not responsible for this disease.
Alias Names Pro-neuregulin-2, membrane-bound isoform, Pro-NRG2, Neuregulin-2, NRG-2, Divergent of neuregulin-1, DON-1, Neural- and thymus-derived activator for ERBB kinases, NTAK, NRG2, NTAK
Product Type Antibodies Primary
Research Area Neuroscience
Size 400 µl
Source / Host rabbit
Species Reactivity human
Substrate / Buffer Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Technical Specifications This NRG2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 358-389 amino acids from the C-terminal region of human NRG2.
Product Page Updated 2019-11-20T10:06:15.280Z

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