Article No
AP2602b
MW | 34880 |
NCBI Number | NP_001047.1;NP_789795.1 |
Accession Number | O00338 |
Application | WB |
Article No | AP2602b |
Country Availability | SE, FI, DK, NO, IS, EE, LV, LT, FO, GL |
Clone | RB5129 |
Clone Type | polyclonal |
Conjugation | Unconjugated |
Description | SULT1C1 Antibody (Center) |
Recommended Dilution | 1:1000 |
Supplier | Abgent |
Entrez Gene ID | 6819 |
Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS. |
Isotype | IgG |
Keywords | Primary Antibodies;Metabolism;Signal Transduction |
Notes | The 296-amino acid human SULTC1 protein, so named on the basis of its significant homology to a rat hepatic cytosolic sulfotranserase ST1C1, catalyzes the sulfate conjugation of many drugs, xenobiotic compounds, hormones, and neurotransmitters, and may be involved in the activation of carcinogenic hydroxylamines. This enzyme also shows activity towards p-nitrophenol and N-hydroxy-2-acetylamino-fluorene (N-OH-2AAF). SULT1C1 is expressed as a 1.4-kb mRNA in adult human stomach, kidney, and thyroid, and in fetal kidney and liver. By functional characterization of recombinant protein, it has been shown that SULT1C1 catalyzes the sulfonation of p-nitrophenol and N-hydroxy-2-acetylaminofluorene, but not dopamine, 17-beta-estradiol, or dehydroepiandrosterone. |
Alias Names | Sulfotransferase 1C2, ST1C2, 282-, Sulfotransferase 1C1, SULT1C#1, humSULTC2, SULT1C2, SULT1C1 |
Product Type | Antibodies Primary |
Research area | Metabolism |
Size | 400 µl |
Source / Host | rabbit |
Species Reactivity | human, mouse |
Substrate / Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS. |
Technical Specifications | This SULT1C1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 95-127 amino acids from the Central region of human SULT1C1. |
Product Page Updated | 2023-11-23T14:38:54.086Z |