Article No
AP22388d-ev
Anti-SARS-CoV-2 Spike glycoprotein antibody
Anti-SARS-CoV-2 Spike glycoprotein antibody (P540)
Antibodies Primary
Specifications
| MW | 141178 |
| Accession Number | P0DTC2 |
| Application | ELISA |
| Article No | AP22388d-ev |
| Country Availability | SE, FI, DK, NO, IS, EE, LV, LT, FO, GL |
| Clone | R00247-250 |
| Clone Type | polyclonal |
| Conjugation | Unconjugated |
| Description | Anti-SARS-CoV-2 Spike glycoprotein antibody (P540) |
| Supplier | Abgent |
| Entrez Gene ID | 43740568 |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Isotype | IgG |
| Notes | The spike (S) glycoprotein of coronaviruses is known to be essential in the binding of the virus to the host cell at the advent of the infection process. It's been reported that 2019-nCoV can infect the human respiratory epithelial cells through interaction with the human ACE2 receptor. The spike protein is a large type I transmembrane protein containing two subunits, S1 and S2. S1 mainly contains a receptor binding domain (RBD), which is responsible for recognizing the cell surface receptor. S2 contains basic elements needed for the membrane fusion.The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity. The main functions for the Spike protein are summarized as: Mediate receptor binding and membrane fusion; Defines the range of the hosts and specificity of the virus; Main component to bind with the neutralizing antibody; Key target for vaccine design; Can be transmitted between different hosts through gene recombination or mutation of the receptor binding domain (RBD), leading to a higher mortality rate. |
| Product Type | Antibodies Primary |
| Size | 80 µl |
| Source / Host | rabbit |
| Substrate / Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Product Page Updated | 2023-11-23T14:38:54.086Z |
