Article No
AP21922b
Specifications
| MW | 31932 |
| Accession Number | Q9HAN9 |
| Application | WB |
| Article No | AP21922b |
| Country Availability | SE, FI, DK, NO, IS, EE, LV, LT, FO, GL |
| Clone | RB55363 |
| Clone Type | polyclonal |
| Conjugation | Unconjugated |
| Description | NMNAT1 Antibody (C-Term) |
| Recommended Dilution | 1:2000 |
| Supplier | Abgent |
| Entrez Gene ID | 64802 |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Isotype | IgG |
| Keywords | Primary Antibodies;Metabolism;Neuroscience;Signal Transduction |
| Notes | Catalyzes the formation of NAD(+) from nicotinamide mononucleotide (NMN) and ATP. Can also use the deamidated form; nicotinic acid mononucleotide (NaMN) as substrate with the same efficiency. Can use triazofurin monophosphate (TrMP) as substrate. Also catalyzes the reverse reaction, i.e. the pyrophosphorolytic cleavage of NAD(+). For the pyrophosphorolytic activity, prefers NAD(+) and NAAD as substrates and degrades NADH, nicotinic acid adenine dinucleotide phosphate (NHD) and nicotinamide guanine dinucleotide (NGD) less effectively. Fails to cleave phosphorylated dinucleotides NADP(+), NADPH and NAADP(+). Protects against axonal degeneration following mechanical or toxic insults. |
| Alias Names | Nicotinamide mononucleotide adenylyltransferase 1, NMN adenylyltransferase 1, 2.7.7.1, Nicotinate-nucleotide adenylyltransferase 1, NaMN adenylyltransferase 1, 2.7.7.18, NMNAT1, NMNAT |
| Product Type | Antibodies Primary |
| Research area | Metabolism |
| Size | 200 µl |
| Source / Host | rabbit |
| Species Reactivity | human |
| Substrate / Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Technical Specifications | This NMNAT1 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 200-232 amino acids from human NMNAT1. |
| Product Page Updated | 2023-11-23T14:38:54.086Z |
