Antibodies Primary

LRPPRC

NEW
LRPPRC Antibody (Center)

Article No

AP21869c-ev

Application

WB

Species Reactivity

human
mouse

Size

50 µl

Clone

RB53981

Source / Host

rabbit

Product insert

Suggested protocols

Specifications

MW 157905
Application WB
Article No AP21869c-ev
Country Availability SE, FI, DK, NO, IS, EE, LV, LT, FO, GL
Clone RB53981
Clone Type polyclonal
Description LRPPRC Antibody (Center)
Recommended Dilution 1:2000
Supplier Abgent
Isotype Ig
Keywords Primary Antibodies;Neuroscience
Notes May play a role in RNA metabolism in both nuclei and mitochondria. In the nucleus binds to HNRPA1-associated poly(A) mRNAs and is part of nmRNP complexes at late stages of mRNA maturation which are possibly associated with nuclear mRNA export. May bind mature mRNA in the nucleus outer membrane. In mitochondria binds to poly(A) mRNA. Plays a role in translation or stability of mitochondrially encoded cytochrome c oxidase (COX) subunits. May be involved in transcription regulation. Cooperates with PPARGC1A to regulate certain mitochondrially encoded genes and gluconeogenic genes and may regulate docking of PPARGC1A to transcription factors. Seems to be involved in the transcription regulation of the multidrug-related genes MDR1 and MVP. Part of a nuclear factor that binds to the invMED1 element of MDR1 and MVP gene promoters. Binds single-stranded DNA (By similarity).
Alias Names Leucine-rich PPR motif-containing protein, mitochondrial, 130 kDa leucine-rich protein, LRP 130, GP130, LRPPRC, LRP130
Product Type Antibodies Primary
Research Area Neuroscience
Size 50 µl
Source / Host rabbit
Species Reactivity human, mouse
Substrate / Buffer Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Technical Specifications This LRPPRC antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 847-876 amino acids from the Central region of human LRPPRC.
Product Page Updated 2019-11-20T10:06:15.280Z

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