Article No
AP21086a-ev
Pdx1 Antibody
(Mouse) Pdx1 Antibody (Center)
Antibodies Primary
Specifications
| MW | 30999 |
| Accession Number | P52946 |
| Application | WB, IF |
| Article No | AP21086a-ev |
| Country Availability | SE, FI, DK, NO, IS, EE, LV, LT, FO, GL |
| Clone | RB51197 |
| Clone Type | polyclonal |
| Conjugation | Unconjugated |
| Description | (Mouse) Pdx1 Antibody (Center) |
| Recommended Dilution | 1:25 |
| Supplier | Abgent |
| Entrez Gene ID | 18609 |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Isotype | IgG |
| Keywords | Crown Antibodies;Primary Antibodies;Cancer;Cardiovascular;Developmental Biology;Signal Transduction;Stem Cells |
| Notes | Activates insulin and somatostatin gene transcription. Key regulator of islet peptide hormone expression but also responsible for the development of the pancreas, most probably by determining maturation and differentiation of common pancreatic precursor cells in the developing gut. As part of a PDX1:PBX1b:MEIS2b complex in pancreatic acinar cells is involved in the transcriptional activation of the ELA1 enhancer; the complex binds to the enhancer B element and cooperates with the transcription factor 1 complex (PTF1) bound to the enhancer A element. Binds the DNA sequence 5'-CC[CT]TAATGGG-3'. |
| Alias Names | Pancreas/duodenum homeobox protein 1, Insulin promoter factor 1, IPF-1, Islet/duodenum homeobox 1, IDX-1, Somatostatin-transactivating factor 1, STF-1, Pdx1, Ipf1 |
| Product Type | Antibodies Primary |
| Size | 80 µl |
| Source / Host | rabbit |
| Species Reactivity | mouse |
| Substrate / Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Technical Specifications | This Mouse Pdx1 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 136-169 amino acids from the Central region of Mouse Pdx1. |
| Product Page Updated | 2023-11-23T14:38:54.086Z |
