Article No
AP2019B
MW | 25454 |
NCBI Number | NP_004307.2 |
Accession Number | P50553 |
Application | WB |
Article No | AP2019B |
Country Availability | SE, FI, DK, NO, IS, EE, LV, LT, FO, GL |
Clone | RB02899 |
Clone Type | polyclonal |
Conjugation | Unconjugated |
Description | ASCL1 (Achaete-scute homolog 1) Antibody (C-term) |
Recommended Dilution | 1:1000 |
Supplier | Abgent |
Entrez Gene ID | 429 |
Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS. |
Isotype | IgG |
Keywords | Primary Antibodies;Neuroscience |
Notes | ACSL1, alternatively titled Hash1 or Mash1, is a member of the basic helix-loop-helix (BHLH) family of transcription factors. It activates transcription by binding to the E box (5'-CANNTG-3'). Dimerization with other BHLH proteins is required for efficient DNA binding. ACSL1 plays a role in the neuronal commitment and differentiation and in the generation of olfactory and autonomic neurons. The protein is highly expressed in medullary thyroid cancer and small cell lung cancer and may be a useful marker for these cancers. The presence of a CAG repeat in the gene suggests it may also play a role in tumor formation. |
Alias Names | Achaete-scute homolog 1, ASH-1, hASH1, Class A basic helix-loop-helix protein 46, bHLHa46, ASCL1, ASH1, BHLHA46, HASH1 |
Product Type | Antibodies Primary |
Research area | Neuroscience |
Size | 400 µl |
Source / Host | rabbit |
Species Reactivity | human, mouse |
Substrate / Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS. |
Technical Specifications | This ASCL1 (Achaete-scute homolog 1) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 166-196 amino acids from the C-terminal region of human ASCL1 (Achaete-scute homolog 1). |
Product Page Updated | 2023-11-23T14:38:54.086Z |