Article No
AP19190a
MW | 76107 |
NCBI Number | NP_116124.2;NP_689652.2 |
Accession Number | Q8N1M1 |
Application | WB |
Article No | AP19190a |
Country Availability | SE, FI, DK, NO, IS, EE, LV, LT, FO, GL |
Clone | RB39849 |
Clone Type | polyclonal |
Conjugation | Unconjugated |
Description | BEST3 Antibody (N-term) |
Recommended Dilution | 1:1000 |
Supplier | Abgent |
Entrez Gene ID | 144453 |
Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
Isotype | IgG |
Keywords | Primary Antibodies;Metabolism;Signal Transduction |
Notes | BEST3 belongs to the bestrophin family of anion channels, which includes BEST1 (MIM 607854), the gene mutant in vitelliform macular dystrophy (VMD; MIM 153700), and 2 other BEST1-like genes, BEST2 (MIM 607335) and BEST4 (MIM 607336). Bestrophins are transmembrane (TM) proteins that share a homology region containing a high content of aromatic residues, including an invariant arg-phe-pro (RFP) motif. The bestrophin genes share a conserved gene structure, with almost identical sizes of the 8 RFP-TM domain-encoding exons and highly conserved exon-intron boundaries. Each of the 4 bestrophin genes has a unique 3-prime end of variable length (Stohr et al., 2002 [PubMed 12032738]; Tsunenari et al., 2003 [PubMed 12907679]). |
Alias Names | Bestrophin-3, Vitelliform macular dystrophy 2-like protein 3, BEST3, VMD2L3 |
Product Type | Antibodies Primary |
Research Area | Metabolism |
Size | 400 µl |
Source / Host | rabbit |
Species Reactivity | human |
Substrate / Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
Technical Specifications | This BEST3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 40-68 amino acids from the N-terminal region of human BEST3. |
Product Page Updated | 2023-11-23T14:38:54.086Z |