Article No
AP18214C-ev
MW | 102952 |
NCBI Number | NP_061723.1;NP_113598.1;NP_113599.1 |
Accession Number | Q9Y5I3 |
Application | WB |
Article No | AP18214C-ev |
Country Availability | SE, FI, DK, NO, IS, EE, LV, LT, FO, GL |
Clone | RB32960 |
Clone Type | polyclonal |
Conjugation | Unconjugated |
Description | PCDHA1 Antibody (Center) |
Recommended Dilution | 1:1000 |
Supplier | Abgent |
Entrez Gene ID | 56147 |
Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
Isotype | IgG |
Keywords | Primary Antibodies;Neuroscience;Signal Transduction |
Notes | This gene is a member of the protocadherin alpha gene cluster, one of three related gene clusters tandemly linked on chromosome five that demonstrate an unusual genomic organization similar to that of B-cell and T-cell receptor gene clusters. The alpha gene cluster is composed of 15 cadherin superfamily genes related to the mouse CNR genes and consists of 13 highly similar and 2 more distantly related coding sequences. The tandem array of 15 N-terminal exons, or variable exons, are followed by downstream C-terminal exons, or constant exons, which are shared by all genes in the cluster. The large, uninterrupted N-terminal exons each encode six cadherin ectodomains while the C-terminal exons encode the cytoplasmic domain. These neural cadherin-like cell adhesion proteins are integral plasma membrane proteins that most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been observed and additional variants have been suggested but their full-length nature has yet to be determined. |
Alias Names | Protocadherin alpha-1, PCDH-alpha-1, PCDHA1 |
Product Type | Antibodies Primary |
Research Area | Neuroscience |
Size | 80 µl |
Source / Host | rabbit |
Species Reactivity | human |
Substrate / Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
Technical Specifications | This PCDHA1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 288-316 amino acids from the Central region of human PCDHA1. |
Product Page Updated | 2023-11-23T14:38:54.086Z |