Antibodies Primary

CRYGB

NEW
CRYGB Antibody (Center)

Article No

AP16201c

Application

WB

Species Reactivity

human

Size

400 µl

Clone

RB35633

Source / Host

rabbit

Product insert

Suggested protocols

Specifications

MW 20908
NCBI Number NP_005201.2
Application WB
Article No AP16201c
Country Availability SE, FI, DK, NO, IS, EE, LV, LT, FO, GL
Clone RB35633
Clone Type polyclonal
Description CRYGB Antibody (Center)
Recommended Dilution 1:1000
Supplier Abgent
Isotype Ig
Keywords Primary Antibodies;Neuroscience
Notes Crystallins are separated into two classes: taxon-specific, or enzyme, and ubiquitous. The latter class constitutes the major proteins of vertebrate eye lens and maintains the transparency and refractive index of the lens. Since lens central fiber cells lose their nuclei during development, these crystallins are made and then retained throughout life, making them extremely stable proteins. Mammalian lens crystallins are divided into alpha, beta, and gamma families; beta and gamma crystallins are also considered as a superfamily. Alpha and beta families are further divided into acidic and basic groups. Seven protein regions exist in crystallins: four homologous motifs, a connecting peptide, and N- and C-terminal extensions. Gamma-crystallins are a homogeneous group of highly symmetrical, monomeric proteins typically lacking connecting peptides and terminal extensions. They are differentially regulated after early development. Four gamma-crystallin genes (gamma-A through gamma-D) and three pseudogenes (gamma-E, gamma-F, gamma-G) are tandemly organized in a genomic segment as a gene cluster. Whether due to aging or mutations in specific genes, gamma-crystallins have been involved in cataract formation.
Alias Names Gamma-crystallin B, Gamma-B-crystallin, Gamma-crystallin 1-2, CRYGB, CRYG2
Product Type Antibodies Primary
Research Area Neuroscience
Size 400 µl
Source / Host rabbit
Species Reactivity human
Substrate / Buffer Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Technical Specifications This CRYGB antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 68-97 amino acids from the Central region of human CRYGB.
Product Page Updated 2019-11-20T10:06:15.280Z

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