Article No
AP1548a
MW | 48229 |
Accession Number | P48165 |
Application | WB |
Article No | AP1548a |
Country Availability | SE, FI, DK, NO, IS, EE, LV, LT, FO, GL |
Clone | RB1381 |
Clone Type | polyclonal |
Conjugation | Unconjugated |
Description | Connexin 50 Antibody (N-term) |
Supplier | Abgent |
Entrez Gene ID | 2703 |
Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS. |
Isotype | IgG |
Keywords | Primary Antibodies;Neuroscience;Signal Transduction |
Notes | GJA8 is a an integral membrane protein that belongs to the connexin family, alpha-type (group II) subfamily. One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. A connexon is composed of a hexamer of connexins. This particular connexin only forms junctional channels. GJA8 is expressed in the eye lens, and defects in GJA8 are the cause of zonular pulverulent cataract type 1 (CZP1), a form of autosomal dominant congenital cataract. |
Alias Names | Gap junction alpha-8 protein, Connexin-50, Cx50, Lens fiber protein MP70, GJA8 |
Product Type | Antibodies Primary |
Research Area | Neuroscience |
Size | 400 µl |
Source / Host | rabbit |
Species Reactivity | human |
Substrate / Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS. |
Technical Specifications | This Connexin 50 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 99-130 amino acids from the N-terminal region of human Connexin 50. |
Product Page Updated | 2023-11-23T14:38:54.086Z |