Antibodies Primary

PCDHGA3

NEW
PCDHGA3 Antibody (Center)

Article No

AP13611C

Application

WB, IHC-P, FC

Species Reactivity

human

Size

400 µl

Clone

RB33029

Source / Host

rabbit

Suggested protocols

Specifications

MW 100971
Application WB, IHC-P, FC
Article No AP13611C
Country Availability DK, EE, FI, FO, GL, IS, LT, LV, NO, SE
Clone RB33029
Clone Type polyclonal
Description PCDHGA3 Antibody (Center)
Supplier Abgent
Keywords Primary Antibodies;Neuroscience;Signal Transduction
Notes This gene is a member of the protocadherin gamma gene cluster, one of three related clusters tandemly linked on chromosome five. These gene clusters have an immunoglobulin-like organization, suggesting that a novel mechanism may be involved in their regulation and expression. The gamma gene cluster includes 22 genes divided into 3 subfamilies. Subfamily A contains 12 genes, subfamily B contains 7 genes and 2 pseudogenes, and the more distantly related subfamily C contains 3 genes. The tandem array of 22 large, variable region exons are followed by a constant region, containing 3 exons shared by all genes in the cluster. Each variable region exon encodes the extracellular region, which includes 6 cadherin ectodomains and a transmembrane region. The constant region exons encode the common cytoplasmic region. These neural cadherin-like cell adhesion proteins most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been described for the gamma cluster genes.
Alias Names Protocadherin gamma-A3, PCDH-gamma-A3, PCDHGA3
Product Type Antibodies Primary
Research Area Neuroscience
Size 400 µl
Source / Host rabbit
Species Reactivity human
Substrate / Buffer Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Technical Specifications This PCDHGA3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 284-311 amino acids from the Central region of human PCDHGA3.
Product Page Updated 2019-10-17T06:10:49.462Z

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