Article No
AP13549b-ev
Specifications
| MW | 55406 |
| NCBI Number | NP_000874.2;NP_001096075.1;NP_001136045.1;NP_001136046.1;NP_001136047.1;NP_001136048.1;NP_899066.1 |
| Accession Number | P20839 |
| Application | WB, IF |
| Article No | AP13549b-ev |
| Country Availability | SE, FI, DK, NO, IS, EE, LV, LT, FO, GL |
| Clone | RB33810 |
| Clone Type | polyclonal |
| Conjugation | Unconjugated |
| Description | IMPDH1 Antibody (C-term) |
| Recommended Dilution | 1:10~50 |
| Supplier | Abgent |
| Entrez Gene ID | 3614 |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Isotype | IgG |
| Keywords | Primary Antibodies;Metabolism;Neuroscience;Signal Transduction |
| Notes | The protein encoded by this gene acts as a homotetramer to regulate cell growth. The encoded protein is an enzyme that catalyzes the synthesis of xanthine monophosphate (XMP) from inosine-5'-monophosphate (IMP). This is the rate-limiting step in the de novo synthesis of guanine nucleotides. Defects in this gene are a cause of retinitis pigmentosa type 10 (RP10). Several transcript variants encoding different isoforms have been found for this gene. |
| Alias Names | Inosine-5'-monophosphate dehydrogenase 1 {ECO:0000255|HAMAP-Rule:MF_03156}, IMP dehydrogenase 1 {ECO:0000255|HAMAP-Rule:MF_03156}, IMPD 1 {ECO:0000255|HAMAP-Rule:MF_03156}, IMPDH 1 {ECO:0000255|HAMAP-Rule:MF_03156}, 111205 {ECO:0000255|HAMAP-Rule:MF_03156}, IMPDH-I, IMPDH1 {ECO:0000255|HAMAP-Rule:MF_03156}, IMPD1 |
| Product Type | Antibodies Primary |
| Research area | Metabolism |
| Size | 80 µl |
| Source / Host | rabbit |
| Species Reactivity | human |
| Substrate / Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Technical Specifications | This IMPDH1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 487-514 amino acids from the C-terminal region of human IMPDH1. |
| Product Page Updated | 2023-11-23T14:38:54.086Z |
