Article No
AP12186c
MW | 49705 |
NCBI Number | NP_065135.2 |
Accession Number | Q9GZZ6 |
Application | WB |
Article No | AP12186c |
Country Availability | SE, FI, DK, NO, IS, EE, LV, LT, FO, GL |
Clone | RB32240 |
Clone Type | polyclonal |
Conjugation | Unconjugated |
Description | CHRNA10 Antibody (Center) |
Recommended Dilution | 1:1000 |
Supplier | Abgent |
Entrez Gene ID | 57053 |
Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
Isotype | IgG |
Keywords | Primary Antibodies;Neuroscience;Signal Transduction |
Notes | CHRNA10 is an ionotropic receptor with a probable role in the modulation of auditory stimuli. Agonist binding may induce an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane. The channel is permeable to a range of divalent cations including calcium, the influx of which may activate a potassium current which hyperpolarizes the cell membrane. In the ear, this may lead to a reduction in basilar membrane motion, altering the activity of auditory nerve fibers and reducing the range of dynamic hearing. This may protect against acoustic trauma. |
Alias Names | Neuronal acetylcholine receptor subunit alpha-10, Nicotinic acetylcholine receptor subunit alpha-10, NACHR alpha-10, CHRNA10, NACHRA10 |
Product Type | Antibodies Primary |
Research Area | Neuroscience |
Size | 400 µl |
Source / Host | rabbit |
Species Reactivity | human |
Substrate / Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
Technical Specifications | This CHRNA10 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 179-206 amino acids from the Central region of human CHRNA10. |
Product Page Updated | 2023-11-23T14:38:54.086Z |