Article No
AP11079c
Specifications
| MW | 57727 |
| NCBI Number | NP_000374.1 |
| Accession Number | O43918 |
| Application | WB, IF |
| Article No | AP11079c |
| Country Availability | SE, FI, DK, NO, IS, EE, LV, LT, FO, GL |
| Clone | RB30050 |
| Clone Type | polyclonal |
| Conjugation | Unconjugated |
| Description | AIRE Antibody (Center) |
| Recommended Dilution | 1:10~50 |
| Supplier | Abgent |
| Entrez Gene ID | 326 |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Isotype | IgG |
| Keywords | Primary Antibodies;Immunology |
| Notes | This gene encodes a transcriptional regulator that forms nuclear bodies and interacts with the transcriptional coactivator CBP. At least three splice variant mRNAs products have been described including one which results in a premature stop codon and a transcript predicted to be a candidate for nuclear-mediated decay (NMD). Defects in this gene cause the rare autosomal-recessive systemic autoimmune disease termed autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy (APECED). |
| Alias Names | Autoimmune regulator, Autoimmune polyendocrinopathy candidiasis ectodermal dystrophy protein, APECED protein, AIRE, APECED |
| Product Type | Antibodies Primary |
| Research area | Immunology |
| Size | 400 µl |
| Source / Host | rabbit |
| Species Reactivity | human |
| Substrate / Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Technical Specifications | This AIRE antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 64-92 amino acids from the Central region of human AIRE. |
| Product Page Updated | 2023-11-23T14:38:54.086Z |
