Article No
AP10456c
Specifications
| MW | 13389 |
| NCBI Number | NP_004427.1;NP_996925.1;NP_996926.1;NP_996927.1;NP_996928.1;NP_996929.1;NP_996930.1;NP_997051.1 |
| Accession Number | O43768 |
| Application | FC, WB |
| Article No | AP10456c |
| Country Availability | SE, FI, DK, NO, IS, EE, LV, LT, FO, GL |
| Clone | RB19622 |
| Clone Type | polyclonal |
| Conjugation | Unconjugated |
| Description | ENSA Antibody (Center) |
| Recommended Dilution | 1:1000 |
| Supplier | Abgent |
| Entrez Gene ID | 2029 |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Isotype | IgG |
| Keywords | Primary Antibodies;Neuroscience |
| Notes | ENSA belongs to a highly conserved cAMP-regulated phosphoprotein (ARPP) family. This protein was identified as an endogenous ligand for the sulfonylurea receptor, ABCC8/SUR1. ABCC8 is the regulatory subunit of the ATP-sensitive potassium (KATP) channel, which is located on the plasma membrane of pancreatic beta cells and plays a key role in the control of insulin release from pancreatic beta cells. This protein is thought to be an endogenous regulator of KATP channels. In vitro studies have demonstrated that this protein modulates insulin secretion through the interaction with KATP channel, and this gene has been proposed as a candidate gene for type 2 diabetes. |
| Alias Names | Alpha-endosulfine, ARPP-19e, ENSA |
| Product Type | Antibodies Primary |
| Research area | Neuroscience |
| Size | 400 µl |
| Source / Host | rabbit |
| Species Reactivity | human, mouse |
| Substrate / Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Technical Specifications | This ENSA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 39-66 amino acids from the Central region of human ENSA. |
| Product Page Updated | 2023-11-23T14:38:54.086Z |
