Antibodies Primary

AKR1C3

NEW
AKR1C3 Antibody (N-term)

Article No

AP10158A

Application

WB, FC

Species Reactivity

human

Size

400 µl

Clone

RB22754

Source / Host

rabbit

Suggested protocols

Specifications

MW 36853
Application WB, FC
Article No AP10158A
Clone RB22754
Clone Type polyclonal
Description AKR1C3 Antibody (N-term)
Supplier Abgent
Keywords Primary Antibodies;Metabolism;Neuroscience;Signal Transduction
Notes This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. These enzymes catalyze the conversion of aldehydes and ketones to their corresponding alcohols by utilizing NADH and/or NADPH as cofactors. The enzymes display overlapping but distinct substrate specificity. This enzyme catalyzes the reduction of prostaglandin (PG) D2, PGH2 and phenanthrenequinone (PQ), and the oxidation of 9alpha,11beta-PGF2 to PGD2. It may play an important role in the pathogenesis of allergic diseases such as asthma, and may also have a role in controlling cell growth and/or differentiation. This gene shares high sequence identity with three other gene members and is clustered with those three genes at chromosome 10p15-p14.
Alias Names Aldo-keto reductase family 1 member C3, 1---, 17-beta-hydroxysteroid dehydrogenase type 5, 17-beta-HSD 5, 3-alpha-HSD type II, brain, 3-alpha-hydroxysteroid dehydrogenase type 2, 3-alpha-HSD type 2, Chlordecone reductase homolog HAKRb, Dihydrodiol dehydrogenase 3, DD-3, DD3, Dihydrodiol dehydrogenase type I, HA1753, Indanol dehydrogenase, Prostaglandin F synthase, PGFS, Testosterone 17-beta-dehydrogenase 5, Trans-1,2-dihydrobenzene-1,2-diol dehydrogenase, AKR1C3, DDH1, HSD17B5, KIAA0119, PGFS
Product Type Antibodies Primary
Research Area Metabolism
Size 400 µl
Source / Host rabbit
Species Reactivity human
Substrate / Buffer Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Technical Specifications This AKR1C3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 10-36 amino acids from the N-terminal region of human AKR1C3.

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