Article No
ANC-573-030
Article No | ANC-573-030 |
Country Availability | SE, FI, DK, NO, IS, EE, LV, LT |
Conjugation | Biotin |
Description | CD273 [B7-DC/PD-L2] (human)-muIg Fusion Protein (Biotin) |
Supplier | Adipogen Life Sciences |
Format | Liquid |
Notes | CD273 (B7-DC; PD-L2) is a type I surface molecule with homology to CD80, CD86, CD274. It is expressed primarily by dendritic cells and provides a stimulatory signal to CD279 (PD-1; programmed death molecule) which has an important immunoregulatory role by downregulating the T cell response. CD273 binds to CD279 (PD-1) with a 2-6 fold higher affinity than CD274.|Protein. Liquid. 50 mM Sodium Phosphate pH 7.5, 100 mM Potassium Chloride, 150mM NaCl, 5% Glycerol, 0.2% BSA, 0.04% NaN3 (as a preservative). CD273 (B7-DC; PD-L2) is a type I surface molecule with homology to CD80, CD86, CD274. It is expressed primarily by dendritic cells and provides a stimulatory signal to CD279 (PD-1; programmed death molecule) which has an important immunoregulatory role by downregulating the T cell response. CD273 binds to CD279 (PD-1) with a 2-6 fold higher affinity than CD274. |
Alias Names | B7-DC; Programmed Cell Death 1 Ligand 2; PD-L2; PDCD1 Ligand 2 |
Product Type | Proteins & Peptides |
Research area | Immunology |
Shipping Information | BLUE ICE |
Size | 25 µg |
Source / Host | human |
Species Reactivity | human |
Stability | Stable for at least 6 months after receipt when stored at +4°C. |
Storage | 4°C |
Substrate / Buffer | 50 mM Sodium Phosphate pH 7.5, 100 mM Potassium Chloride, 150mM NaCl, 5% Glycerol, 0.2% BSA, 0.04% NaN3 (as a preservative). |
Technical Specifications | Protein. Liquid. 50 mM Sodium Phosphate pH 7.5, 100 mM Potassium Chloride, 150mM NaCl, 5% Glycerol, 0.2% BSA, 0.04% NaN3 (as a preservative). CD273 (B7-DC; PD-L2) is a type I surface molecule with homology to CD80, CD86, CD274. It is expressed primarily by dendritic cells and provides a stimulatory signal to CD279 (PD-1; programmed death molecule) which has an important immunoregulatory role by downregulating the T cell response. CD273 binds to CD279 (PD-1) with a 2-6 fold higher affinity than CD274. |
Product Page Updated | 2024-02-01T08:25:01.492Z |