Article No
ANC-368-040
Application | ELISA, FC |
Article No | ANC-368-040 |
Country Availability | SE, FI, DK, NO, IS, EE, LV, LT |
Clone | ANC5E3 |
Clone Type | monoclonal |
Conjugation | FITC |
Description | anti-CD357 [GITR] (human), mAb (ANC5E3) (FITC) |
Supplier | Adipogen Life Sciences |
Format | Liquid |
Immunogen | Recombinant human GITR, PHA stimulated human PBL. |
Isotype | IgG3 k |
Notes | Glucocorticoid induced TNF receptor family related gene (GITR; AITR) is a type 1 228 amino acid transmembrane protein that has been designated TNFRSF18. GITR is expressed mainly by CD4+ CD25+ T lymphocytes. Its engagement by antibodies or its ligand (GITRL) induces a costimulatory signal which can break T cell suppression. GITR has been implicated as a regulatory mechanism in anti-parasitic immune resposes, and is involved with macrophages activation in atherosclerotic plaque formation.|Monoclonal Antibody. Isotype: Mouse IgG3kappa. Clone: ANC5E3. Applications: ELISA, FACS. 50 mM Sodium Phosphate pH 7.5, 500 mM Potassium Chloride, 150mM NaCl, 5% Glycerol, 0.2% BSA, 0.04% NaN3 (as a preservative). Glucocorticoid induced TNF receptor family related gene (GITR; AITR) is a type 1 228 amino acid transmembrane protein that has been designated TNFRSF18. GITR is expressed mainly by CD4+ CD25+ T lymphocytes. Its engagement by antibodies or its ligand (GITRL) induces a costimulatory signal which can break T cell suppression. GITR has been implicated as a regulatory mechanism in anti-parasitic immune resposes, and is involved with macrophages activation in atherosclerotic plaque formation. |
Alias Names | GITR; Glucocorticoid-induced TNF Receptor; AITR; Activation-inducible TNF-related; Tumor Necrosis Factor Receptor Superfamily Member 18; TNFRSF18 |
Product Type | Antibodies Primary |
Research Area | Immunology |
Shipping Information | BLUE ICE |
Size | 120 tests |
Source / Host | mouse |
Species Reactivity | human |
Stability | Stable for at least 1 year after receipt when stored at +4°C. |
Storage | 4°C |
Substrate / Buffer | 50 mM Sodium Phosphate pH 7.5, 500 mM Potassium Chloride, 150mM NaCl, 5% Glycerol, 0.2% BSA, 0.04% NaN3 (as a preservative). |
Technical Specifications | Monoclonal Antibody. Isotype: Mouse IgG3kappa. Clone: ANC5E3. Applications: ELISA, FACS. 50 mM Sodium Phosphate pH 7.5, 500 mM Potassium Chloride, 150mM NaCl, 5% Glycerol, 0.2% BSA, 0.04% NaN3 (as a preservative). Glucocorticoid induced TNF receptor family related gene (GITR; AITR) is a type 1 228 amino acid transmembrane protein that has been designated TNFRSF18. GITR is expressed mainly by CD4+ CD25+ T lymphocytes. Its engagement by antibodies or its ligand (GITRL) induces a costimulatory signal which can break T cell suppression. GITR has been implicated as a regulatory mechanism in anti-parasitic immune resposes, and is involved with macrophages activation in atherosclerotic plaque formation. |
Product Page Updated | 2024-02-01T08:25:01.492Z |