Article No
ANC-273-820
anti-CD273 [B7-DC/PD-L2] (human), mAb (ANC8D12) (preservative free)
anti-CD273 [B7-DC/PD-L2] (human), mAb (ANC8D12) (preservative free)
Antibodies Primary
Specifications
| Application | Block, ELISA, FC |
| Article No | ANC-273-820 |
| Country Availability | SE, FI, DK, NO, IS, EE, LV, LT |
| Clone | ANC8D12 |
| Clone Type | monoclonal |
| Conjugation | Unconjugated |
| Description | anti-CD273 [B7-DC/PD-L2] (human), mAb (ANC8D12) (preservative free) |
| Supplier | Adipogen Life Sciences |
| Format | Liquid |
| Immunogen | Recombinant human CD273. |
| Isotype | IgG2a k |
| Notes | CD273 (B7-DC; PD-L2) is a type I surface molecule with homology to CD80, CD86, CD274. It is expressed primarily by dendritic cells and provides a stimulatory signal to CD279 (PD-1; Programmed Cell Death 1) which has an important immunoregulatory role by downregulating the T cell response. CD273 binds to CD279 (PD-1) with a 2-6 fold higher affinity than CD274 and is an important component of immune regulation.|Monoclonal Antibody. Isotype: Mouse IgG2akappa. Clone: ANC8D12. Applications: ELISA, FACS, FUNC (Blocking). 50mM Sodium Phosphate pH 7.5, 100mM Potassium Chloride, 150mM NaCl. CD273 (B7-DC; PD-L2) is a type I surface molecule with homology to CD80, CD86, CD274. It is expressed primarily by dendritic cells and provides a stimulatory signal to CD279 (PD-1; Programmed Cell Death 1) which has an important immunoregulatory role by downregulating the T cell response. CD273 binds to CD279 (PD-1) with a 2-6 fold higher affinity than CD274 and is an important component of immune regulation. |
| Alias Names | Programmed Death Ligand 2 |
| Product Type | Antibodies Primary |
| Purity | >95% |
| Research area | Immunology |
| Shipping Information | BLUE ICE |
| Size | 100 µg |
| Source / Host | mouse |
| Species Reactivity | human |
| Stability | Stable for at least 1 year after receipt when stored at +4°C. |
| Storage | 4°C |
| Substrate / Buffer | 50mM Sodium Phosphate pH 7.5, 100mM Potassium Chloride, 150mM NaCl. |
| Technical Specifications | Monoclonal Antibody. Isotype: Mouse IgG2akappa. Clone: ANC8D12. Applications: ELISA, FACS, FUNC (Blocking). 50mM Sodium Phosphate pH 7.5, 100mM Potassium Chloride, 150mM NaCl. CD273 (B7-DC; PD-L2) is a type I surface molecule with homology to CD80, CD86, CD274. It is expressed primarily by dendritic cells and provides a stimulatory signal to CD279 (PD-1; Programmed Cell Death 1) which has an important immunoregulatory role by downregulating the T cell response. CD273 binds to CD279 (PD-1) with a 2-6 fold higher affinity than CD274 and is an important component of immune regulation. |
| Product Page Updated | 2024-02-01T08:25:01.492Z |
