Article No
AMB-LTFXX5-100
ACVR1 Primary Antibody
ACVR1 Primary Antibody
Antibodies Primary
Specifications
| MW | 57.2kDa |
| Application | WB |
| Article No | AMB-LTFXX5-100 |
| Biosite Brand | Biosite mAb |
| Country Availability | all |
| Clone | 2E2C11 |
| Clone Type | monoclonal |
| Conjugation | Unconjugated |
| Description | ACVR1 Primary Antibody |
| Supplier | Nordic Biosite |
| Format | Purified antibody in PBS with 0.05% sodium azide |
| Immunogen | Purified recombinant fragment of human ACVR1 (AA: 21-120) expressed in E. Coli. |
| Isotype | IgG1 |
| Notes | Activins are dimeric growth and differentiation factors which belong to the transforming growth factor-beta (TGF-beta) superfamily of structurally related signaling proteins. Activins signal through a heteromeric complex of receptor serine kinases which include at least two type I ( I and IB) and two type II (II and IIB) receptors. These receptors are all transmembrane proteins, composed of a ligand-binding extracellular domain with cysteine-rich region, a transmembrane domain, and a cytoplasmic domain with predicted serine/threonine specificity. Type I receptors are essential for signaling; and type II receptors are required for binding ligands and for expression of type I receptors. Type I and II receptors form a stable complex after ligand binding, resulting in phosphorylation of type I receptors by type II receptors. This gene encodes activin A type I receptor which signals a particular transcriptional response in concert with activin type II receptors. Mutations in this gene are associated with fibrodysplasia ossificans progressive. |
| Alias Names | FOP; ALK2; SKR1; TSRI; ACTRI; ACVR1A; ACVRLK2 |
| Product Type | Antibodies Primary |
| Protocol | ELISA: 1/10000; WB: 1/500 - 1/2000; ICC: 1/200 - 1/1000; FCM: 1/200 - 1/400; IHC: 1/200 - 1/1000 |
| Size | 100µl |
| Source / Host | mouse |
| Species Reactivity | human |
| Storage | 4°C -20°C for long term storage |
| Substrate / Buffer | Purified antibody in PBS with 0.05% sodium azide |
| Product Page Updated | 2024-01-25T14:27:54.645Z |
