HLA-DRA

Article No AMB-F72279
Product Type Antibodies Primary
Application ELISA, WB, ICC, FC
Size 0.1mg

Specifications

MW 58.8kDa
Country Availability all
BioSite Brand BioSite mAb
Clone 1C11A5;
Clone Type monoclonal
Description Mouse Monoclonal Antibody to HLA-DRA
Supplier BioSite Mab
Entrez Gene ID 3858
Immunogen Purified recombinant fragment of human HLA-DRA (AA: 26-254) expressed in E. Coli.
Isotype IgG2b
Notes HLA-DRA is one of the HLA class II alpha chain paralogues. This class II molecule is a heterodimer consisting of an alpha and a beta chain, both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). The alpha chain is approximately 33-35 kDa and its gene contains 5 exons. Exon 1 encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, and exon 4 encodes the transmembrane domain and the cytoplasmic tail. DRA does not have polymorphisms in the peptide binding part and acts as the sole alpha chain for DRB1, DRB3, DRB4 and DRB5. ;
Alias Names BIE; EHK; K10; KPP; BCIE; CK10
Protocol ELISA: 1/10000; WB: 1/500 - 1/2000; IHC: ; ICC: 1/100 - 1/500; FCM: 1/200 - 1/400
Source / Host mouse
Species Reactivity human
Storage 4 C, -20 C for long term storage
Substrate / Buffer Purified antibody in PBS with 0.05% sodium azide
Technical Specifications ELISA: 1/10000; WB: 1/500 - 1/2000; IHC: ; ICC: 1/100 - 1/500; FCM: 1/200 - 1/400
Product Page Updated 2018-10-15T09:15:17.802Z

Shipping info

The delivery time for this item is approximately 5-8 business days. If other deviations occur, this will be noted on the order confirmation or communicated via email. Please note, we do reserve the right to select the best packaging and shipping method in order to insure the stability of the product and allow efficient order tracking.

Source/Host:

mouse mouse

Species reactivity:

human human

Suggested protocols:

Western Blot

Western Blot