Phospho-4E-BP1 (Ser65)

Article No AMB-F04216
Product Type Antibodies Primary
Application ELISA, ICC, FC, IHC
Size 0.1mg

Specifications

MW 12.6kDa
Country Availability all
BioSite Brand BioSite mAb
Clone 2D1G11
Clone Type monoclonal
Description Phospho-4E-BP1 (Ser65)
Supplier BioSite Mab
Entrez Gene ID 1978
Immunogen Synthesized peptide of human Phospho-4E-BP1 (Ser65).
Isotype IgG1
Notes This gene encodes one member of a family of translation repressor proteins. The protein directly interacts with eukaryotic translation initiation factor 4E (eIF4E), which is a limiting component of the multisubunit complex that recruits 40S ribosomal subunits to the 5' end of mRNAs. Interaction of this protein with eIF4E inhibits complex assembly and represses translation. This protein is phosphorylated in response to various signals including UV irradiation and insulin signaling, resulting in its dissociation from eIF4E and activation of mRNA translation.
Alias Names EIF4EBP1; BP-1; 4EBP1; 4E-BP1; PHAS-I
Protocol ELISA: 1/10000; WB: N/A; ICC: N/A; FCM: 1/200 - 1/400; IHC: 1/200 - 1/1000
Source / Host mouse
Species Reactivity human
Storage 4 C, -20 C for long term storage
Substrate / Buffer Purified antibody in PBS with 0.05% sodium azide
Technical Specifications ELISA: 1/10000; WB: N/A; ICC: N/A; FCM: 1/200 - 1/400; IHC: 1/200 - 1/1000
Product Page Updated 2018-10-15T09:15:17.802Z

Shipping info

The delivery time for this item is approximately 5-8 business days. If other deviations occur, this will be noted on the order confirmation or communicated via email. Please note, we do reserve the right to select the best packaging and shipping method in order to insure the stability of the product and allow efficient order tracking.

Source/Host:

mouse mouse

Species reactivity:

human human

Suggested protocols:

IHC-P

IHC-P