Antibodies Primary

CD191

NEW
CD191

Article No

AMB-DC0951

Application

ELISA, WB, ICC, FC

Species Reactivity

human

Size

0.1mg

Clone

8E10G6

Source / Host

mouse

Suggested protocols

Specifications

MW 41.2kDa
Application ELISA, WB, ICC, FC
Article No AMB-DC0951
BioSite Brand BioSite mAb
Clone 8E10G6
Clone Type monoclonal
Description CD191
Supplier BioSite Mab
Entrez Gene ID 1230
Immunogen Purified recombinant fragment of human CD191 (AA: extra mix) expressed in E. Coli.
Isotype IgG1
Notes This gene encodes a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. The ligands of this receptor include macrophage inflammatory protein 1 alpha (MIP-1 alpha), regulated on activation normal T expressed and secreted protein (RANTES), monocyte chemoattractant protein 3 (MCP-3), and myeloid progenitor inhibitory factor-1 (MPIF-1). Chemokines and their receptors mediated signal transduction are critical for the recruitment of effector immune cells to the site of inflammation. Knockout studies of the mouse homolog suggested the roles of this gene in host protection from inflammatory response, and susceptibility to virus and parasite. This gene and other chemokine receptor genes, including CCR2, CCRL2, CCR3, CCR5 and CCXCR1, are found to form a gene cluster on chromosome 3p.
Alias Names CCR1; CKR1; CKR-1; HM145; CMKBR1; MIP1aR; SCYAR1
Product Type Antibodies Primary
Protocol ELISA: 1/10000; WB: 1/500 - 1/2000; ICC: N/A; FCM: 1/200 - 1/400; IHC: N/A
Size 0.1mg
Source / Host mouse
Species Reactivity human
Storage 4°C -20°C for long term storage
Substrate / Buffer Purified antibody in PBS with 0.05% sodium azide
Technical Specifications ELISA: 1/10000; WB: 1/500 - 1/2000; ICC: N/A; FCM: 1/200 - 1/400; IHC: N/A
Product Page Updated 2019-08-02T12:49:54.081Z

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