Antibodies Primary

PSMC3

NEW
Mouse Monoclonal Antibody to PSMC3

Article No

AMB-9381

Application

ELISA, WB, IHC, ICC, FC

Species Reactivity

human
monkey
rat

Size

0.1mg

Clone

1G10B7;

Source / Host

mouse

Suggested protocols

Specifications

MW 49kDa
Application ELISA, WB, IHC, ICC, FC
Article No AMB-9381
BioSite Brand BioSite mAb
Clone 1G10B7;
Clone Type monoclonal
Description Mouse Monoclonal Antibody to PSMC3
Supplier BioSite Mab
Entrez Gene ID 5702
Immunogen Purified recombinant fragment of human PSMC3 (AA: 53-152) expressed in E. Coli.
Isotype IgG1
Notes The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes one of the ATPase subunits, a member of the triple-A family of ATPases that have chaperone-like activity. This subunit may compete with PSMC2 for binding to the HIV tat protein to regulate the interaction between the viral protein and the transcription complex. A pseudogene has been identified on chromosome 9.;
Alias Names TBP1
Product Type Antibodies Primary
Protocol ELISA: 1/10000; WB: 1/500 - 1/2000; IHC: 1/200 - 1/1000; ICC: 1/200 - 1/1000; FCM: 1/200 - 1/400
Size 0.1mg
Source / Host mouse
Species Reactivity human, monkey, rat
Storage 4 C, -20 C for long term storage
Substrate / Buffer Purified antibody in PBS with 0.05% sodium azide
Technical Specifications ELISA: 1/10000; WB: 1/500 - 1/2000; IHC: 1/200 - 1/1000; ICC: 1/200 - 1/1000; FCM: 1/200 - 1/400
Product Page Updated 2018-10-15T09:15:17.802Z

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