TIE1

Article No AMB-8991
Product Type Antibodies Primary
Application ELISA, WB, IHC
Size 0.1mg

Specifications

MW 125kDa
Country Availability all
BioSite Brand BioSite mAb
Clone 8D12B10;
Clone Type monoclonal
Description Mouse Monoclonal Antibody to TIE1
Supplier BioSite Mab
Entrez Gene ID 7075
Immunogen Purified recombinant fragment of human TIE1 (AA: 385-607) expressed in E. Coli.
Isotype IgG1
Notes This gene encodes a member of the tyrosine protein kinase family. The encoded protein plays a critical role in angiogenesis and blood vessel stability by inhibiting angiopoietin 1 signaling through the endothelial receptor tyrosine kinase Tie2. Ectodomain cleavage of the encoded protein relieves inhibition of Tie2 and is mediated by multiple factors including vascular endothelial growth factor. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.r;
Alias Names TIE; JTK14
Protocol ELISA: 1/10000; WB: 1/500 - 1/2000; IHC: 1/200 - 1/1000
Source / Host mouse
Species Reactivity human
Storage 4 C, -20 C for long term storage
Substrate / Buffer Purified antibody in PBS with 0.05% sodium azide.
Technical Specifications ELISA: 1/10000; WB: 1/500 - 1/2000; IHC: 1/200 - 1/1000
Product Page Updated 2018-10-15T09:15:17.802Z

Shipping info

The delivery time for this item is approximately 5-8 business days. If other deviations occur, this will be noted on the order confirmation or communicated via email. Please note, we do reserve the right to select the best packaging and shipping method in order to insure the stability of the product and allow efficient order tracking.

Source/Host:

mouse mouse

Species reactivity:

human human

Suggested protocols:

Western Blot

Western Blot

IHC-P

IHC-P