PLAGL1

Article No AMB-8911
Product Type Antibodies Primary
Application ELISA, WB, IHC
Size 0.1mg

Specifications

MW 50.8kDa
Country Availability all
BioSite Brand BioSite mAb
Clone 8D8C5;
Clone Type monoclonal
Description Mouse Monoclonal Antibody to PLAGL1
Supplier BioSite Mab
Entrez Gene ID 5325
Immunogen Purified recombinant fragment of human PLAGL1 (AA: 118-222) expressed in E. Coli.
Isotype IgG1
Notes This gene encodes a C2H2 zinc finger protein with transactivation and DNA-binding activities. It has been shown to have anti-proliferative properties, and thus thought to function as a tumor suppressor. In addition, overexpression of this gene during fetal development is believed to underlie the rare disorder, transient neonatal diabetes mellitus (TNDM). This gene is imprinted, with preferential expression of the paternal allele in many tissues, however, biallelic expression has been noted in peripheral blood leucocytes. A recent study reports that tissue-specific imprinting results from variable utilization of monoallelic and biallelic promoters. Many transcript variants differing in the 5' UTR and encoding two different isoforms, have been found for this gene.  ;
Alias Names ZAC; LOT1; ZAC1
Protocol ELISA: 1/10000; WB: 1/500 - 1/2000; IHC: 1/200 - 1/1000
Source / Host mouse
Species Reactivity human
Storage 4 C, -20 C for long term storage
Substrate / Buffer Purified antibody in PBS with 0.05% sodium azide
Technical Specifications ELISA: 1/10000; WB: 1/500 - 1/2000; IHC: 1/200 - 1/1000
Product Page Updated 2018-10-15T09:15:17.802Z

Shipping info

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Source/Host:

mouse mouse

Species reactivity:

human human

Suggested protocols:

Western Blot

Western Blot

IHC-P

IHC-P