Antibodies Primary

CYP3A4

NEW
Mouse Monoclonal Antibody to CYP3A4

Article No

AMB-8782

Application

ELISA, WB, IHC, ICC, FC

Species Reactivity

human

Size

0.1mg

Clone

3H8;

Source / Host

mouse

Suggested protocols

Specifications

MW 57.3kDa
Application ELISA, WB, IHC, ICC, FC
Article No AMB-8782
BioSite Brand BioSite mAb
Clone 3H8;
Clone Type monoclonal
Description Mouse Monoclonal Antibody to CYP3A4
Supplier BioSite Mab
Entrez Gene ID 1576
Immunogen Purified recombinant fragment of human CYP3A4 expressed in E. Coli. ;
Isotype IgG1
Notes This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases that catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by glucocorticoids and some pharmacological agents. This enzyme is involved in the metabolism of approximately half the drugs in use today, including acetaminophen, codeine, cyclosporin A, diazepam and erythromycin. The enzyme also metabolizes some steroids and carcinogens. This gene is part of a cluster of cytochrome P450 genes on chromosome 7q21.1. Previously another CYP3A gene, CYP3A3, was thought to exist; however, it is now thought that this sequence represents a transcript variant of CYP3A4. Alternatively spliced transcript variants encoding different isoforms have been identified.
Alias Names HLP; CP33; CP34; CYP3A; NF-25; CYP3A3; P450C3; CYPIIIA3; CYPIIIA4; P450PCN1
Product Type Antibodies Primary
Protocol ELISA: 1/10000; WB: 1/500 - 1/2000; IHC: 1/200 - 1/1000; ICC: 1/200 - 1/1000; FCM: 1/200 - 1/400
Size 0.1mg
Source / Host mouse
Species Reactivity human
Storage 4°C -20°C for long term storage
Substrate / Buffer Purified antibody in PBS with 0.05% sodium azide
Technical Specifications ELISA: 1/10000; WB: 1/500 - 1/2000; IHC: 1/200 - 1/1000; ICC: 1/200 - 1/1000; FCM: 1/200 - 1/400
Product Page Updated 2019-08-02T12:49:54.081Z

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