HEXA

Article No AMB-8779
Product Type Antibodies Primary
Application ELISA, WB, FC
Size 0.1mg

Specifications

MW 60.7kDa
Country Availability all
BioSite Brand BioSite mAb
Clone 3F10;
Clone Type monoclonal
Description Mouse Monoclonal Antibody to HEXA
Supplier BioSite Mab
Entrez Gene ID 3073
Immunogen Purified recombinant fragment of human HEXA expressed in E. Coli. ;
Isotype IgG2b
Notes This gene encodes the alpha subunit of the lysosomal enzyme beta-hexosaminidase that, together with the cofactor GM2 activator protein, catalyzes the degradation of the ganglioside GM2, and other molecules containing terminal N-acetyl hexosamines. Beta-hexosaminidase is composed of two subunits, alpha and beta, which are encoded by separate genes. Both beta-hexosaminidase alpha and beta subunits are members of family 20 of glycosyl hydrolases. Mutations in the alpha or beta subunit genes lead to an accumulation of GM2 ganglioside in neurons and neurodegenerative disorders termed the GM2 gangliosidoses. Alpha subunit gene mutations lead to Tay-Sachs disease (GM2-gangliosidosis type I).
Alias Names TSD
Protocol ELISA: 1/10000; WB: 1/500 - 1/2000; FCM: 1/200 - 1/400
Source / Host mouse
Species Reactivity human
Storage 4 C, -20 C for long term storage
Substrate / Buffer Purified antibody in PBS with 0.05% sodium azide
Technical Specifications ELISA: 1/10000; WB: 1/500 - 1/2000; FCM: 1/200 - 1/400
Product Page Updated 2018-10-15T09:15:17.802Z

Shipping info

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Source/Host:

mouse mouse

Species reactivity:

human human

Suggested protocols:

Western Blot

Western Blot