Article No
AMB-6IK6OZ-100
MSH6 Primary Antibody
MSH6 Primary Antibody
Antibodies Primary
Specifications
| MW | 160kDa |
| Application | WB, ELISA, FC, ICC |
| Article No | AMB-6IK6OZ-100 |
| Biosite Brand | Biosite mAb |
| Country Availability | all |
| Clone | 3E1 |
| Clone Type | monoclonal |
| Conjugation | Unconjugated |
| Description | MSH6 Primary Antibody |
| Supplier | Nordic Biosite |
| Entrez Gene ID | 2956 |
| Format | Ascitic fluid containing 0.03% sodium azide.<br /> |
| Immunogen | Purified recombinant fragment of human MSH6 expressed in E. Coli. |
| Isotype | IgG2a |
| Notes | This gene encodes a protein similar to the MutS protein. In E. coli, the MutS protein helps in the recognition of mismatched nucleotides, prior to their repair. A highly conserved region of approximately 150 aa, called the Walker-A adenine nucleotide binding motif, exists in MutS homologs. The encoded protein of this gene combines with MSH2 to form a mismatch recognition complex that functions as a bidirectional molecular switch that exchanges ADP and ATP as DNA mismatches are bound and dissociated. Mutations in this gene have been identified in individuals with hereditary nonpolyposis colon cancer (HNPCC) and endometrial cancer. |
| Alias Names | GTBP; HSAP; HNPCC5 |
| Previous Article No | AMB-8735 |
| Product Type | Antibodies Primary |
| Protocol | ELISA: 1/10000; WB: 1/500 - 1/2000; IHC: 1/200 - 1/1000; ICC: 1/200 - 1/1000; FCM: 1/200 - 1/400 |
| Size | 100µl |
| Source / Host | mouse |
| Species Reactivity | human |
| Storage | 4°C -20°C for long term storage |
| Substrate / Buffer | Ascitic fluid containing 0.03% sodium azide.; |
| Technical Specifications | ELISA: 1/10000; WB: 1/500 - 1/2000; IHC: 1/200 - 1/1000; ICC: 1/200 - 1/1000; FCM: 1/200 - 1/400 |
| Product Page Updated | 2024-01-25T14:27:22.065Z |
