Antibodies Primary

KIT

NEW
Mouse Monoclonal Antibody to KIT

Article No

AMB-8695

Application

ELISA, WB, IHC

Species Reactivity

human

Size

100μl

Clone

1C5;

Source / Host

mouse

Suggested protocols

Specifications

MW 145kDa
Application ELISA, WB, IHC
Article No AMB-8695
BioSite Brand BioSite mAb
Clone 1C5;
Clone Type monoclonal
Description Mouse Monoclonal Antibody to KIT
Supplier BioSite Mab
Entrez Gene ID 3815
Immunogen Purified recombinant fragment of human KIT expressed in E. Coli. ;
Isotype IgG1
Notes The c-Kit proto-oncogene is a member of the receptor tyrosine kinase family and, more specifically, is closely related to the platelet derived growth factor receptor (PDGFR). c-Kit, the normal cellular homolog of the HZ4-feline sarcoma virus transforming gene (v-Kit), encodes a transmembrane receptor. c-Kit regulates a variety of biological responses including chemotaxis, cell prolif- eration, apoptosis and adhesion. c-Kit is also identical with the product of the W locus in mice and, as such, is integral to the development of mast cells and hematopoiesis. The ligand for the c-Kit receptor (KL) has been identified and is encoded at the murine steel (SI) locus. Kit is the human homolog of the proto- oncogene c-Kit. Mutations in Kit are integral for tumor growth and progression in various cancers.
Alias Names PBT; SCFR; C-Kit; CD117
Product Type Antibodies Primary
Protocol ELISA: 1/10000; WB: 1/500 - 1/2000; IHC: 1/200 - 1/1000
Size 100μl
Source / Host mouse
Species Reactivity human
Storage 4°C -20°C for long term storage
Substrate / Buffer Ascitic fluid containing 0.03% sodium azide.
Technical Specifications ELISA: 1/10000; WB: 1/500 - 1/2000; IHC: 1/200 - 1/1000
Product Page Updated 2019-08-02T12:49:54.081Z

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