Article No
AMB-N95YIR-100
MW | 72kDa |
Application | WB, ELISA, FC, ICC |
Article No | AMB-N95YIR-100 |
Biosite Brand | Biosite mAb |
Country Availability | all |
Clone | 3G8 |
Clone Type | monoclonal |
Conjugation | Unconjugated |
Description | ABCG2 Primary Antibody |
Supplier | Nordic Biosite |
Entrez Gene ID | 9429 |
Format | Ascitic fluid containing 0.03% sodium azide. |
Immunogen | Purified recombinant fragment of human ABCG2 expressed in E. Coli. |
Isotype | IgG1 |
Notes | The membrane-associated protein encoded by this gene is included in the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the White subfamily. Alternatively referred to as a breast cancer resistance protein, this protein functions as a xenobiotic transporter which may play a major role in multi-drug resistance. It likely serves as a cellular defense mechanism in response to mitoxantrone and anthracycline exposure. Significant expression of this protein has been observed in the placenta, which may suggest a potential role for this molecule in placenta tissue.Tissue specificity: Highly expressed in placenta. Low expression in small intestine, liver and colon. |
Alias Names | MRX; MXR; ABCP; BCRP; BMDP; MXR1; ABC15; BCRP1; CD338; CDw338; EST157481; MGC102821 |
Previous Article No | AMB-8652 |
Product Type | Antibodies Primary |
Protocol | ELISA: 1/10000; WB: 1/500 - 1/2000; IHC: 1/200 - 1/1000; ICC: 1/200 - 1/1000; FCM: 1/200 - 1/400 |
Size | 100µl |
Source / Host | mouse |
Species Reactivity | human, mouse, monkey |
Storage | 4°C -20°C for long term storage |
Substrate / Buffer | Ascitic fluid containing 0.03% sodium azide. |
Technical Specifications | ELISA: 1/10000; WB: 1/500 - 1/2000; IHC: 1/200 - 1/1000; ICC: 1/200 - 1/1000; FCM: 1/200 - 1/400 |
Product Page Updated | 2024-01-25T14:27:22.065Z |